01
Pipelines others can re-run
Nextflow and nf-core workflows built to community standards, tested with nf-test, and FAIR from the first commit.
$ whoami
I build programs, games & science.
Hi, I’m Chris: a bioinformatician from Bristol. I write reproducible pipelines and software, make games, study how evolution works, and travel whenever I can.
Pipelines I’ve built and contributed to recently (click one to see it)
N E X T F L O WLaunching `chriswyatt/profile` [focused_darwin]executor > local (6)
[3f/a1c2e4]genomeqc✓ 1 of 1[9b/77e05d]synteny✓ 1 of 1[c4/0d19aa]excon✓ 1 of 1[e2/5b8c31]dietary_amplicons✓ 1 of 1[71/c09f4e]pollen-metabarcoding✓ 1 of 1[a8/3e62d7]nanoporemetabarcoding✓ 1 of 1
Completed at: 13-Nov-2026Succeeded : 6I’m researching synteny in social insects: how genes have moved around the genome over time
- nextflow
- nf-core
- nf-test
- docker
- singularity
- conda
- unix / bash
- R
- python
- perl
- git
- RNA-Seq
- proteomics
- synteny
- gene families
- phylogenetics
- metabarcoding
- alternative splicing
20peer-reviewed papers + 5 preprints
6open-source pipelines, nf-core standards
£612kBBSRC programme · lead bioinformatician
published inNature · Nature Communications · PNAS · Science Advances
// what i bring
all workSkills, from raw reads to results
02
Comparative genomics
Genome and annotation quality, synteny, gene-family expansion and contraction, phylogenetics and molecular evolution.
03
Multi-omics, end to end
RNA-Seq, proteomics, genomic and phenotypic data, from alternative splicing to machine-learning models.
04
Teaching & community
nf-core hackathons, multi-day Nextflow workshops, and contributions to the official Nextflow training material.
// pipelines
github.com/eco-flowPipelines I’ve built
$ nextflow run nf-core/genomeqc
Genome quality
genomeqc
Compare the quality of many genome assemblies and their annotations in one run. Now part of nf-core, and described in a 2026 preprint.
$ nextflow run eco-flow/synteny
Genome structure
synteny
Synteny analysis across genomes: trace conserved gene order and chromosome rearrangements between species.
$ nextflow run eco-flow/excon
Gene families
excon
Measure gene-family expansion and contraction across a phylogeny of species.
+ metabarcoding:dietary_ampliconspollen-metabarcodingnanoporemetabarcodingtaxonomic profiling from amplicon and nanopore reads
// on github
github.com/chriswyatt1What I’m writing
2,308 contributions in the last year
- active days
- 219in the last year
- longest streak
- 36days in a row
- current streak
- 0days
- busiest day
- 4428 September
| language | all time | last year | last 3 months |
|---|---|---|---|
| Nextflow | 49% | 42% | 25% |
| Perl | 11% | 2.1% | 3.0% |
| R | 8.3% | 10% | 7.1% |
| Python | 8.1% | 15% | 35% |
| Dockerfile | 8.0% | 2.3% | – |
| HTML | 7.0% | 14% | 13% |
| CSS | 3.2% | 7.0% | 9.2% |
| Other | 5.3% | 6.6% | 7.6% |
Calendar: my GitHub contributions. Languages: my commits across public repos, each split by lines changed. Updated 2026-11-13.
// off the clock
Organisms, wild places & travel
~/organisms
Organisms I’ve worked on
A field guide to the organisms behind my genomics work, from bumblebees and paper wasps to amphioxus and early embryos.
organisms~/travel
Places I’ve called home
6 places I’ve called home across 4 countries, plus 226 more I’ve visited.
travel~/notes · latest
How this site works
A static Astro site on GitHub Pages, publications that update themselves from ORCID, and a map that flies between the places I've lived.
read the note// publications
all 25Selected papers
- 2026
- 2023Social complexity, life-history and lineage influence the molecular basis of castes in vespid wasps
Nature Communications, 14(1), 1046
- 2022
- 2018Amphioxus functional genomics and the origins of vertebrate gene regulation
Nature, 564(7734), 64-70